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ROCK inhibitor-2
CAS No. 1127308-52-4
ROCK inhibitor-2( —— )
Catalog No. M23320 CAS No. 1127308-52-4
ROCK inhibitor-2 is a selective dual inhibitor of ROCK1 and ROCK2 (IC50s of 17 nM and 2 nM, respectively).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 97 | In Stock |
|
| 5MG | 160 | In Stock |
|
| 10MG | 259 | In Stock |
|
| 25MG | 520 | In Stock |
|
| 50MG | 750 | In Stock |
|
| 100MG | 1035 | In Stock |
|
| 500MG | 2061 | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameROCK inhibitor-2
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NoteResearch use only, not for human use.
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Brief DescriptionROCK inhibitor-2 is a selective dual inhibitor of ROCK1 and ROCK2 (IC50s of 17 nM and 2 nM, respectively).
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DescriptionROCK inhibitor-2 is a selective dual inhibitor of ROCK1 and ROCK2 (IC50s of 17 nM and 2 nM, respectively).
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayCell Cycle/DNA Damage
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TargetROCK
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RecptorROCK1|ROCK2
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Research Area——
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Indication——
Chemical Information
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CAS Number1127308-52-4
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Formula Weight332.4
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Molecular FormulaC21H20N2O2
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Purity>98% (HPLC)
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SolubilityDMSO:250 mg/mL (752.11 mM; Need ultrasonic)
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SMILESO=C(N[C@@H](C1=CC=CC(OC)=C1)C)C2=CC=C(C3=CC=NC=C3)C=C2
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Hobson AD, et al. Identification of Selective Dual ROCK1 and ROCK2 Inhibitors Using Structure-Based DrugDesign. J Med Chem. 2018 Dec 27;61(24):11074-11100.
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ROCK inhibitor-2
ROCK inhibitor-2 is a selective dual inhibitor of ROCK1 and ROCK2 (IC50s of 17 nM and 2 nM, respectively).
